Diseases /

Carcinoma

Back to Diseases List
Associated Genetic Biomarkers

Overview

NCI Definition: A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. [1]

Clinical Trials

View Clinical Trials for Carcinoma

Significant Genes in Carcinoma

ERBB2 +

Disease Details

Synonyms
Carcinoma, NOS, Epithelial Carcinoma, Malignant Epithelioma, Malignant Epithelial Tumor, Epithelioma Malignant, Poorly Differentiated Carcinoma, Malignant Epithelial Neoplasm, CARCINOMA, MALIGNANT
Parent(s)
Malignant Solid Tumor
Children
Prostate Carcinoma, Papillary Carcinoma, Carcinoma of Unknown Primary, Vulvar/Vaginal Carcinoma, Granular Cell Carcinoma, Cervical Carcinoma, Choroid Plexus Carcinoma, Primary Peritoneal Carcinoma, Large Cell Carcinoma, Retroperitoneal Carcinoma, Adenosquamous Carcinoma, Adenoid Cystic Carcinoma, Tracheal Carcinoma, Sarcomatoid Carcinoma, Acinar Cell Carcinoma, Epithelial-Myoepithelial Carcinoma, Kidney Carcinoma, Bladder Carcinoma, Urethral Carcinoma, Lipid-Rich Carcinoma, Digestive System Carcinoma, Ovarian Carcinoma, Cribriform Carcinoma, Metastatic Carcinoma in the Adrenal Medulla, Malignant Myoepithelioma, Skin Carcinoma, Head and Neck Carcinoma, Thyroid Gland Carcinoma, Breast Carcinoma, Transitional Cell Carcinoma, Adenocarcinoma, Penile Carcinoma, Mucoepidermoid Carcinoma, Ureter Carcinoma, Lung Carcinoma, Pleomorphic Carcinoma, Thymic Carcinoma, Endometrial Carcinoma, Metaplastic Carcinoma, Carcinoma In Situ, Squamous Cell Carcinoma, Neuroendocrine Carcinoma, Undifferentiated Carcinoma, Fallopian Tube Carcinoma, and Poorly Differentiated Carcinoma, NOS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.