Overview

NCI Definition: An aggressive diffuse large B-cell lymphoma affecting patients older than 50 years. Epstein-Barr virus is present in all cases. There is no known history of immunodeficiency or prior lymphoma. The majority of patients present with extranodal disease. [1]

Significant Genes in EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

BCL2 +

BCL6 +

MYC +

Disease Details

Synonyms
Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, EBV Positive DLBCL, NOS, EBV-Positive DLBCL, NOS, EBV-Positive Diffuse Large B-Cell Lymphoma, NOS, Epstein-Barr Virus Positive DLBCL, NOS, EBV Positive Diffuse Large B-Cell Lymphoma of the Elderly, Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma of the Elderly, Senile EBV-Associated B-Cell Lymphoproliferative Disorder, Age-Related EBV Positive B-Cell Lymphoproliferative Disorder
Parent(s)
Diffuse Large B-Cell Lymphoma
OncoTree Name
EBV Positive DLBCL, NOS
OncoTree Code
EBVDLBCLNOS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.