Overview

NCI Definition: A morphologic finding indicating tissue infiltration by non-neoplastic or neoplastic histiocytes. [1]

Significant Genes in Histiocytosis

ACBD5 +

AFAP1L2 +

BRAF +

CCDC6 +

CEP43 +

ERC1 +

GOLGA5 +

HOOK3 +

HRAS +

IDH1 +

KIAA1217 +

KIF5B +

NCOA4 +

PPFIBP2 +

PRKAR1A +

RET +

RUFY1 +

TFG +

TRIM27 +

Disease Details

Synonyms
Histiocytic Infiltrate, Soft tissue histiocytosis (NOS), Histiocytic Syndrome, PEDIATRIC Soft tissue histiocytosis (NOS)
Parent(s)
Histiocytic and Dendritic Cell Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.