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Inflammatory Myofibroblastic Tumor

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Associated Genetic Biomarkers

Overview

NCI Definition: A multinodular intermediate fibroblastic neoplasm that arises from soft tissue or viscera, in children and young adults. It is characterized by the presence of spindle-shaped fibroblasts and myofibroblasts, and a chronic inflammatory infiltrate composed of eosinophils, lymphocytes, and plasma cells. [1]

Biomarker-Directed Therapies

View Therapies for Inflammatory Myofibroblastic Tumor

Significant Genes in Inflammatory Myofibroblastic Tumor

ALK +

Disease Details

Synonyms
Soft tissue inflammatory myofibroblastic tumor, PEDIATRIC Soft tissue inflammatory myofibroblastic tumor, Inflammatory Fibrosarcoma, IMT, Inflammatory Pseudotumor, Inflammatory Myofibroblastic Neoplasm
Parent(s)
Fibroblastic Neoplasm
Children
Liver Inflammatory Myofibroblastic Tumor, Lung Inflammatory Myofibroblastic Tumor, and Bladder Inflammatory Myofibroblastic Tumor
OncoTree Name
Inflammatory Myofibroblastic Tumor
OncoTree Code
IMT

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.