Overview

NCI Definition: A high grade malignant neoplasm that arises from the lung and is characterized by the presence of large neuroendocrine cells. It usually has an aggressive clinical course. [1]

Disease Details

Synonyms
Large Cell Neuroendocrine Carcinoma of the Lung, Pulmonary Large Cell Neuroendocrine Carcinoma, LCNEC of the Lung, Large Cell Lung Carcinoma with Neuroendocrine Differentiation, Lung Large Cell Neuroendocrine Carcinoma, Large Cell Neuroendocrine Carcinoma of Lung, Large Cell Neuroendocrine Carcinoma Lung Primary
Parent(s)
Lung Neuroendocrine Carcinoma
Children
Combined Large Cell Lung Neuroendocrine Carcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.