Diseases /

Laryngeal Squamous Cell Carcinoma

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Associated Genetic Biomarkers

Overview

NCI Definition: A squamous cell carcinoma that arises from the larynx. It is the most common histologic type of laryngeal carcinoma. It can arise from the glottis, supraglottic area, or it can be transglottic. Glottic squamous cell carcinoma is the most frequent laryngeal carcinoma in the United States. The symptoms, clinical behavior and the prognosis depend on the site of origin within the larynx. [1]

Clinical Trials

View Clinical Trials for Laryngeal Squamous Cell Carcinoma

Significant Genes in Laryngeal Squamous Cell Carcinoma

CCND1 +

EGFR +

ERBB2 +

Disease Details

Synonyms
Squamous Cell Carcinoma of the Larynx, Epidermoid Carcinoma of Larynx, Larynx Squamous Cell Carcinoma, Laryngeal Epidermoid Carcinoma, Epidermoid Carcinoma of the Larynx, Larynx Epidermoid Carcinoma, Squamous Cell Carcinoma of Larynx
Parent(s)
Laryngeal Carcinoma
Children
Laryngeal Verrucous Carcinoma, Supraglottic Squamous Cell Carcinoma, Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant, Subglottic Squamous Cell Carcinoma, and Glottis Squamous Cell Carcinoma
OncoTree Name
Larynx Squamous Cell Carcinoma
OncoTree Code
LXSC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.