Overview

NCI Definition: A primary or metastatic malignant neoplasm involving the larynx. The majority are carcinomas. [1]

Significant Genes in Malignant Laryngeal Neoplasm

ABL1 +

BRAF +

DDR2 +

EGFR +

EPHA2 +

ERBB2 +

ERBB4 +

FGFR1 +

FGFR2 +

FLT1 +

FLT4 +

FRK +

KDR +

KIT +

MAPK11 +

PDGFRA +

PDGFRB +

RAF1 +

RET +

TEK +

TRNAK2 +

VEGFA +

VEGFB +

VEGFC +

Disease Details

Synonyms
Malignant Tumor of the Larynx, Malignant Larynx Tumor, Malignant Neoplasm of Larynx, Malignant Tumor of Larynx, Malignant Larynx Neoplasm, Malignant Laryngeal Tumor, Malignant Neoplasm of the Larynx
Parent(s)
Malignant Head and Neck Neoplasm
Children
Malignant Glottis Neoplasm, Malignant Supraglottic Neoplasm, Laryngeal Sarcoma, Malignant Subglottic Neoplasm, Laryngeal Carcinoma, and Malignant Supraglottis Neoplasm

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.