Diseases /
Malignant Thyroid Gland Neoplasm
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Associated Genetic Biomarkers
Overview
NCI Definition: A primary or metastatic malignant neoplasm affecting the thyroid gland. [1]
Malignant thyroid gland neoplasms most frequently harbor alterations in BRAF, RET, TP53, NRAS, and CDKN2A [2].
BRAF Mutation, BRAF Exon 15 Mutation, BRAF Codon 600 Missense, BRAF V600E, and NRAS Mutation are the most common alterations in malignant thyroid gland neoplasm [2].
Clinical Trials
Significant Genes in Malignant Thyroid Gland Neoplasm
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.