Overview

NCI Definition: A malignant glandular epithelial neoplasm characterized by the presence of clear and hobnail cells. It is highly associated with ovarian endometriosis, pelvic endometriosis and paraendocrine hypercalcemia. [1]

Significant Genes in Ovarian Clear Cell Adenocarcinoma

ATM +

ATR +

BARD1 +

BRCA1 +

BRCA2 +

BRIP1 +

CHEK1 +

CHEK2 +

FANCA +

FANCB +

FANCC +

FANCD2 +

FANCE +

FANCF +

FANCG +

FANCI +

FANCL +

FANCM +

MCPH1 +

MRE11A +

NBN +

PALB2 +

PTEN +

RAD50 +

RAD51 +

RAD51B +

RAD51C +

RAD51D +

SLX4 +

Disease Details

Synonyms
Ovary clear cell carcinoma
Parent(s)
Ovarian Adenocarcinoma
Children
Ovarian Clear Cell Cystadenocarcinoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.