NCI Definition: An uncommon, indolent B-cell non-Hodgkin lymphoma composed of small B-lymphocytes involving the red pulp of the spleen, bone marrow, and peripheral blood. Patients often have massive splenomegaly. The peripheral blood examination reveals villous lymphocytes. [1]

Significant Genes in Splenic Diffuse Red Pulp Small B-Cell Lymphoma


Disease Details

Splenic B-Cell Lymphoma/Leukemia, Unclassifiable
OncoTree Name
Splenic Diffuse Red Pulp Small B-Cell Lymphoma
OncoTree Code


1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.