Associated Genetic Biomarkers
NCI Definition: An adenocarcinoma arising from the vagina. Morphologic variants include the clear cell, endometrioid, mesonephric, and mucinous adenocarcinoma. 
Vaginal adenocarcinomas most frequently harbor alterations in TP53, LZTR1, FANCA, and ATM .
TP53 c.217-c.1178 Missense, TP53 Y163N, TP53 Mutation, TP53 Missense, and TP53 Exon 5 Mutation are the most common alterations in vaginal adenocarcinoma .
There is 1 clinical trial for vaginal adenocarcinoma, of which 1 is open and 0 are completed or closed. Of the trial that contains vaginal adenocarcinoma as an inclusion criterion, 1 is phase 3 (1 open).
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.