Biomarkers /

G6PD

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Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
Xq28
Protein [2]
Glucose-6-phosphate 1-dehydrogenase
Synonyms [1]
G6PD1

G6PD is altered in 1.27% of all cancers with endometrial endometrioid adenocarcinoma, colon adenocarcinoma, high grade ovarian serous adenocarcinoma, low grade ovarian serous adenocarcinoma, and bladder urothelial carcinoma having the greatest prevalence of alterations [3].

G6PD GENIE Cases - Top Diseases

The most common alterations in G6PD are G6PD Mutation (1.19%), G6PD L203M (0.44%), G6PD R454C (0.77%), G6PD V291M (0.77%), and G6PD A335T (0.39%) [3].

G6PD GENIE Cases - Top Alterations

Clinical Trials

View Clinical Trials for G6PD

Significance of G6PD in Diseases

Ampulla Of Vater Adenocarcinoma +

Pancreatic Adenocarcinoma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.