STRN is altered in 0.13% of all cancers with glioblastoma, lung adenocarcinoma, pancreatic adenocarcinoma, breast invasive ductal carcinoma, and colon adenocarcinoma having the greatest prevalence of alterations .
The most common alterations in STRN are STRN-PDGFRA Fusion (0.17%), STRN-ALK Fusion (0.06%), STRN-NTRK2 Fusion (0.02%), STRN-NTRK3 Fusion (0.03%), and STRN-PTCH1 Fusion (0.01%) .
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.