Biomarkers /
CBFB
Overview
Core-binding factor, beta subunit (CBFB) is a gene that encodes a protein that is the beta subunit in a core-binding transcription factor of the PEBP2/CBF family. The protein functions in the regulation of genes that are involved in hematopoiesis. Fusions, missense and nonsense mutations are observed in cancers such as breast cancer and intestinal cancer.
Clinical Trials
Significance of CBFB in Diseases
References
1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.