Location [1]
Synonyms [1]

FAM175A is altered in 0.54% of all cancers with colon adenocarcinoma, endometrial endometrioid adenocarcinoma, breast invasive ductal carcinoma, lung adenocarcinoma, and prostate adenocarcinoma having the greatest prevalence of alterations [3].

FAM175A GENIE Cases - Top Diseases

The most common alterations in FAM175A are FAM175A Mutation (0.39%), FAM175A Loss (0.06%), FAM175A Amplification (0.05%), FAM175A R285W (0.02%), and FAM175A G3R (0.03%) [3].

FAM175A GENIE Cases - Top Alterations

Significance of FAM175A in Diseases

Malignant Solid Tumor +

Prostate Adenocarcinoma +

Pancreatic Adenocarcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.