Location [1]
Protein [2]
Fibroblast growth factor 18
Synonyms [1]

FGF18 is altered in 0.01% of all cancers with high grade ovarian serous adenocarcinoma, poorly differentiated gastric carcinoma, and testicular non-seminomatous germ cell tumor having the greatest prevalence of alterations [3].

FGF18 GENIE Cases - Top Diseases

The most common alterations in FGF18 are FGF18-NPM1 Fusion (0.01%) and FGF18-RASA1 Fusion (0.00%) [3].

FGF18 GENIE Cases - Top Alterations

Significance of FGF18 in Diseases

Urothelial Carcinoma +

Gastric Carcinoma +

Cancer +

Cholangiocarcinoma +

Endometrial Carcinoma +

Malignant Solid Tumor +

Multiple Myeloma +

Myeloproliferative Neoplasm +

Squamous Cell Lung Carcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.