Location [1]
Protein [2]
Fibroblast growth factor 5
Synonyms [1]
HBGF-5, Smag-82, TCMGLY

FGF5 is altered in 0.78% of all cancers with basal cell carcinoma, colorectal adenocarcinoma, and endometrial carcinoma having the greatest prevalence of alterations [3].

FGF5 GENIE Cases - Top Diseases

The most common alterations in FGF5 are FGF5 Mutation (0.78%), FGF5 A191T (0.26%), FGF5 P204L (0.26%), and FGF5 Q48H (0.26%) [3].

FGF5 GENIE Cases - Top Alterations

Significance of FGF5 in Diseases

Urothelial Carcinoma +

Endometrial Carcinoma +

Malignant Solid Tumor +

Cancer +

Cholangiocarcinoma +

Gastric Carcinoma +

Multiple Myeloma +

Myeloproliferative Neoplasm +

Squamous Cell Lung Carcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.