Biomarkers /

GATA2

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Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
3q21.3
Synonyms [1]
DCML, NFE1B, IMD21, MONOMAC

GATA binding protein 2 (GATA2) is a gene that encodes a zinc-finger transcription factor in the GATA family. Missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame deletions and insertions are observed in cancers such as colorectal cancer, lung cancer, and skin cancer.

Clinical Trials

View Clinical Trials for GATA2

Significance of GATA2 in Diseases

Acute Myeloid Leukemia +

Myelodysplastic Syndrome With Excess Blasts-2 +

Myeloid Neoplasm +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.