Biomarkers /
IL7R
Overview
Interleukin 7 receptor (IL7R) is a gene that encodes a protein that functions as a receptor for interleukin 7. The protein also plays an important role in V(D)J recombination during lymphocyte development. Missense mutations, nonsense mutations, silent mutations, frameshift deletions, and in-frame insertions are observed in cancers such as endometrial cancer, lung cancer, and skin cancer.
Clinical Trials
Significance of IL7R in Diseases
References
1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.