Overview

NCI Definition: The most frequent type of lymphoblastic lymphoma. It comprises approximately 85-90% of cases. It is more frequently seen in adolescent males. It frequently presents with a mass lesion in the mediastinum. Pleural effusions are common. (WHO, 2001) [1]

Significant Genes in T-Cell Lymphoblastic Lymphoma

ABL1 +

ABL2 +

BCR +

CEP72 +

CRLF2 +

EPOR +

FGFR1 +

FGFR2 +

FGFR3 +

FGFR4 +

FLT3 +

IL7R +

JAK1 +

JAK2 +

JAK3 +

LYN +

NTRK1 +

NTRK2 +

NTRK3 +

PDGFRA +

PDGFRB +

SH2B3 +

TYK2 +

Disease Details

Synonyms
T Lymphoblastic Lymphoma
Parent(s)
T-Cell Non-Hodgkin Lymphoma

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.