Nucleoporin 98kDa (NUP98) is a gene that encodes a nucleoporin protein that functions in nuclear transport – the export and import through the nuclear pore complex (NPC). The protein’s specific function may be that of a nucleoporin docking protein. Fusions, missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer.
Modified: July 1, 2015
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