Biomarkers /

RHEB

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Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
7q36.1
Synonyms [1]
RHEB2

Ras homolog enriched in brain (RHEB) is a gene that encodes a lipid-anchored, cell membrane protein. The protein regulates cell growth and cell cycle progression. Missense, nonsense, and silent mutations are observed in cancers such as endometrial cancer, intestinal cancer, and stomach cancer.

Clinical Trials

View Clinical Trials for RHEB

Significance of RHEB in Diseases

B-Cell Non-Hodgkin Lymphoma +

Cancer +

Malignant Solid Tumor +

Multiple Myeloma +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.