Gene Location [1]
Variant Type

Biomarker-Directed Therapies

Significance of SSTR5 Expression in Diseases

Pancreatic Neuroendocrine Tumor +

Small Intestinal Neuroendocrine Tumor +

Gastric Neuroendocrine Tumor +

Colorectal Neuroendocrine Tumor +

Esophageal Neuroendocrine Tumor +

Neuroendocrine Tumor +

Adrenal Gland Pheochromocytoma +

Paraganglioma +

Gastrointestinal Neuroendocrine Tumors +

Lung Neuroendocrine Neoplasm +

Neuroendocrine Carcinoma +

Appendix Neuroendocrine Tumor +

Colorectal Neuroendocrine Neoplasm +

Digestive System Neuroendocrine Neoplasm +

Functional Pancreatic Neuroendocrine Tumor +

Lung Carcinoid Tumor +

Malignant Solid Tumor +

Meningioma +

Neuroblastoma +

Neuroendocrine Carcinoma Of Unknown Primary +

Non-Functioning Pancreatic Endocrine Tumor +

Parathyroid Gland Carcinoma +

Pituitary Gland Carcinoma +

Thymic Neuroendocrine Neoplasm +

Thyroid Gland Medullary Carcinoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.

Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.

4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

5. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.