Overview

NCI Definition: An uncommon carcinoma arising from the cervix. It is composed of malignant glandular epithelial cells and malignant squamous epithelial cells. [1]

Cervical adenosquamous carcinomas most frequently harbor alterations in STK11, PTEN, PIK3CA, PIK3R1, and KRAS [2].

Most Commonly Altered Genes in Cervical Adenosquamous Carcinoma

PIK3CA Mutation, PTEN Mutation, PIK3CA E545K, PIK3CA Codon 545 Missense, and STK11 Mutation are the most common alterations in cervical adenosquamous carcinoma [2].

Top Alterations in Cervical Adenosquamous Carcinoma

Disease Details

Synonyms
Adenosquamous Cell Carcinoma of the Cervix Uteri, Adenosquamous Cell Carcinoma of Cervix Uteri, Adenosquamous Cell Carcinoma of Uterine Cervix, Adenosquamous Cell Carcinoma of Cervix, Adenosquamous Cell Carcinoma of the Uterine Cervix, Uterine Cervix Adenosquamous Cell Carcinoma, Cervical Adenosquamous Cell Carcinoma, Cervix Uteri Adenosquamous Cell Carcinoma, Adenosquamous Cell Carcinoma of the Cervix, Cervix Adenosquamous Cell Carcinoma
Parent(s)
Cervical Carcinoma
Children
Cervical Adenosquamous Carcinoma, Glassy Cell Variant
OncoTree Name
Cervical Adenosquamous Carcinoma
OncoTree Code
CEAS

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.