Diseases /
Cervical Adenosquamous Carcinoma
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Associated Genetic Biomarkers
Overview
NCI Definition: An uncommon carcinoma arising from the cervix. It is composed of malignant glandular epithelial cells and malignant squamous epithelial cells. [1]
Cervical adenosquamous carcinomas most frequently harbor alterations in STK11, PTEN, PIK3CA, PIK3R1, and KRAS [2].
PIK3CA Mutation, PTEN Mutation, PIK3CA E545K, PIK3CA Codon 545 Missense, and STK11 Mutation are the most common alterations in cervical adenosquamous carcinoma [2].
Clinical Trials
Disease Details
References
1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].
2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.