Biomarkers /

CSF3R

Back to Biomarkers List
Associated Genetic Biomarkers
Associated Diseases

Overview

Location [1]
1p34.3
Synonyms [1]
SCN7, CD114, GCSFR

Colony stimulating factor 3 receptor (CSF3R) is a gene that encodes the receptor associated with colony stimulating factor 3, which is a member of the family of cytokine receptors. Missense mutations, nonsense mutations, silent mutations, and frameshift mutations are observed in cancers such as colorectal cancer, leukemias, lung cancer, skin cancer, and stomach cancer.

Clinical Trials

View Clinical Trials for CSF3R

Significance of CSF3R in Diseases

Acute Myeloid Leukemia +

Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative +

Chronic Neutrophilic Leukemia +

Myelodysplastic Syndrome With Excess Blasts-2 +

Myeloid Neoplasm +

References

1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.