Associated Genetic Biomarkers

Overview

NCI Definition: A primary or metastatic malignant neoplasm involving the small intestine. [1]

Significant Genes in Malignant Small Intestinal Neoplasm

ARID1A +

ATM +

ATR +

ATRX +

BARD1 +

BRCA1 +

BRCA2 +

BRIP1 +

C11ORF30 +

CDK12 +

CHEK1 +

CHEK2 +

ERCC2 +

ERCC3 +

ERCC4 +

ERCC5 +

ERCC6 +

FANCA +

FANCB +

FANCC +

FANCD2 +

FANCE +

FANCF +

FANCG +

FANCI +

FANCL +

FANCM +

HDAC1 +

HDAC2 +

KRAS +

MCPH1 +

MDM2 +

MDM4 +

MLF1 +

MLH1 +

MLH3 +

MRE11A +

MSH2 +

MSH3 +

MSH6 +

MUTYH +

NBN +

NPM1 +

PALB2 +

PARP1 +

PARP2 +

PMS1 +

PMS2 +

POLE +

PPP2R1A +

PPP2R2A +

PTEN +

RAD50 +

RAD51 +

RAD51B +

RAD51C +

RAD51D +

RAD54L +

SLX4 +

SMARCB1 +

STAG2 +

STK11 +

TP53 +

XRCC1 +

Disease Details

Synonyms
Malignant Neoplasm of the Small Bowel, Malignant Small Intestine Neoplasm, Malignant Small Bowel Neoplasm, Malignant Tumor of the Small Bowel, Malignant Neoplasm of Small Intestine, Malignant Small Intestine Tumor, Malignant Tumor of the Small Intestine, Malignant Neoplasm of the Small Intestine, Malignant Small Bowel Tumor, Malignant Tumor of Small Intestine, Small Intestine, Malignant Tumor of Small Bowel, Malignant Neoplasm of Small Bowel
Parent(s)
Small Intestinal Neoplasm
Children
Small Intestinal Sarcoma, Malignant Duodenal Neoplasm, Small Intestinal Lymphoma, Jejunal Cancer, and Small Intestinal Carcinoma
OncoTree Name
Small Bowel Cancer
OncoTree Code
SBC

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.