Overview

NCI Definition: Progression of polycythemia vera characterized by decreased erythropoiesis and granulopoiesis, reticulin and collagen fibrosis of the bone marrow, leucoerythroblastic reaction in the peripheral blood, poikilocytosis, tear-drop shaped red blood cells, and splenomegaly. [1]

Disease Details

Synonyms
Spent Phase and Post-Polycythemic Myelofibrosis, Polycythemia Vera, "Spent" Phase, Post-PV MF, Polycythemia Vera, Post-Polycythemic Myelofibrosis and Myeloid Metaplasia Stage, Post-polycythemia Vera Myelofibrosis
Parent(s)
Polycythemia Vera
OncoTree Name
Polycythemia Vera Myelofibrosis
OncoTree Code
PVMF

References

1. National Cancer Institute. NCI Thesaurus Version 18.11d. https://ncit.nci.nih.gov/ncitbrowser/ [2018-08-28]. [2018-09-21].

2. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 4. This dataset does not represent the totality of the genetic landscape; see paper for more information.

3. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.