Biomarkers /
MAPK1
Overview
Mitogen-activated protein kinase 1 (MAPK1) is a gene that encodes a protein that belongs to the MAP kinase family. The protein functions in several cell signaling processes such as proliferation, differentiation, transcriptional regulation, and cellular development. Missense, nonsense, and silent mutations are observed in cancers such as cervical cancer, endometrial cancer, and skin cancer.
Clinical Trials
Significance of MAPK1 in Diseases
References
1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015. https://github.com/biocommons/uta
2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.
3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.
4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.