PDGFRA is altered in 9.75% of gastrointestinal stromal tumor patients [3].

PDGFRA is an inclusion criterion in 15 clinical trials for gastrointestinal stromal tumor, of which 14 are open and 1 is closed. Of the trials that contain PDGFRA status and gastrointestinal stromal tumor as inclusion criteria, 3 are phase 1 (3 open), 1 is phase 1/phase 2 (1 open), 6 are phase 2 (6 open), and 5 are phase 3 (4 open) [4].

Avapritinib, dasatinib, imatinib, and sunitinib have evidence of efficacy in patients with PDGFRA mutation in gastrointestinal stromal tumor [4].

Imatinib has evidence of efficacy in patients with PDGFRA mutation in myelodysplastic/myeloproliferative neoplasm [4].

PDGFRA is altered in 2.54% of malignant solid tumor patients [3].

PDGFRA is an inclusion criterion in 20 clinical trials for malignant solid tumor, of which 16 are open and 4 are closed. Of the trials that contain PDGFRA status and malignant solid tumor as inclusion criteria, 8 are phase 1 (6 open), 4 are phase 1/phase 2 (4 open), and 8 are phase 2 (6 open) [4].

PDGFRA is altered in 3.46% of non-small cell lung carcinoma patients [3].

PDGFRA is an inclusion criterion in 12 clinical trials for non-small cell lung carcinoma, of which 9 are open and 3 are closed. Of the trials that contain PDGFRA status and non-small cell lung carcinoma as inclusion criteria, 2 are phase 1 (2 open), 2 are phase 1/phase 2 (2 open), and 8 are phase 2 (5 open) [4].

PDGFRA is altered in 1.24% of breast carcinoma patients [3].

PDGFRA is an inclusion criterion in 7 clinical trials for breast carcinoma, of which 7 are open and 0 are closed. Of the trials that contain PDGFRA status and breast carcinoma as inclusion criteria, 2 are phase 1 (2 open), 2 are phase 1/phase 2 (2 open), and 3 are phase 2 (3 open) [4].

PDGFRA is altered in 5.63% of melanoma patients [3].

PDGFRA is an inclusion criterion in 4 clinical trials for melanoma, of which 4 are open and 0 are closed. Of the trials that contain PDGFRA status and melanoma as inclusion criteria, 1 is phase 1 (1 open), 2 are phase 1/phase 2 (2 open), and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 2.27% of colorectal carcinoma patients [3].

PDGFRA is an inclusion criterion in 4 clinical trials for colorectal carcinoma, of which 4 are open and 0 are closed. Of the trials that contain PDGFRA status and colorectal carcinoma as inclusion criteria, 1 is phase 1 (1 open), 2 are phase 1/phase 2 (2 open), and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 2.42% of cancer patients [3].

PDGFRA is an inclusion criterion in 4 clinical trials for cancer, of which 2 are open and 2 are closed. Of the trials that contain PDGFRA status and cancer as inclusion criteria, 1 is early phase 1 (0 open), 1 is phase 1 (1 open), and 2 are phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 4 clinical trials for head and neck squamous cell carcinoma, of which 3 are open and 1 is closed. Of the trials that contain PDGFRA status and head and neck squamous cell carcinoma as inclusion criteria, 1 is phase 1 (1 open), 1 is phase 1/phase 2 (1 open), and 2 are phase 2 (1 open) [4].

PDGFRA is altered in 4.79% of small cell lung carcinoma patients [3].

PDGFRA is an inclusion criterion in 3 clinical trials for small cell lung carcinoma, of which 2 are open and 1 is closed. Of the trials that contain PDGFRA status and small cell lung carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 2 are phase 2 (1 open) [4].

PDGFRA is altered in 1.22% of non-hodgkin lymphoma patients [3].

PDGFRA is an inclusion criterion in 3 clinical trials for non-hodgkin lymphoma, of which 3 are open and 0 are closed. Of the trials that contain PDGFRA status and non-hodgkin lymphoma as inclusion criteria, 1 is phase 1 (1 open) and 2 are phase 2 (2 open) [4].

PDGFRA is altered in 0.48% of pancreatic carcinoma patients [3].

PDGFRA is an inclusion criterion in 3 clinical trials for pancreatic carcinoma, of which 3 are open and 0 are closed. Of the trials that contain PDGFRA status and pancreatic carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 2 are phase 2 (2 open) [4].

PDGFRA is altered in 8.68% of glioblastoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for glioblastoma, of which 1 is open and 1 is closed. Of the trials that contain PDGFRA status and glioblastoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (0 open) [4].

PDGFRA is altered in 8.44% of malignant glioma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for malignant glioma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and malignant glioma as inclusion criteria, 1 is phase 1 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 4.78% of squamous cell lung carcinoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for squamous cell lung carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and squamous cell lung carcinoma as inclusion criteria, 1 is phase 1 (1 open) and 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 2.76% of urothelial carcinoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for urothelial carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and urothelial carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 1.23% of ovarian carcinoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for ovarian carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and ovarian carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.9% of gastric adenocarcinoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for gastric adenocarcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and gastric adenocarcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.83% of renal cell carcinoma patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for renal cell carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and renal cell carcinoma as inclusion criteria, 2 are phase 1/phase 2 (2 open) [4].

PDGFRA is altered in 0.67% of myeloid neoplasm patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for myeloid neoplasm, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and myeloid neoplasm as inclusion criteria, 1 is phase 1 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.52% of acute myeloid leukemia patients [3].

PDGFRA is an inclusion criterion in 2 clinical trials for acute myeloid leukemia, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and acute myeloid leukemia as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for adenocarcinoma of the gastroesophageal junction, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and adenocarcinoma of the gastroesophageal junction as inclusion criteria, 2 are phase 2 (2 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for aggressive systemic mastocytosis, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and aggressive systemic mastocytosis as inclusion criteria, 2 are phase 1 (2 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for esophageal carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and esophageal carcinoma as inclusion criteria, 2 are phase 2 (2 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for hepatocellular carcinoma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and hepatocellular carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) and 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for mast cell leukemia, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and mast cell leukemia as inclusion criteria, 2 are phase 1 (2 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for multiple myeloma, of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and multiple myeloma as inclusion criteria, 2 are phase 2 (2 open) [4].

PDGFRA is an inclusion criterion in 2 clinical trials for systemic mastocytosis with an associated hematological neoplasm (SM-AHN), of which 2 are open and 0 are closed. Of the trials that contain PDGFRA status and systemic mastocytosis with an associated hematological neoplasm (SM-AHN) as inclusion criteria, 2 are phase 1 (2 open) [4].

PDGFRA is altered in 4.63% of osteosarcoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for osteosarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and osteosarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 6.7% of glioma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for glioma, of which 0 are open and 1 is closed. Of the trial that contains PDGFRA status and glioma as inclusion criteria, 1 is phase 2 (0 open) [4].

PDGFRA is altered in 3.5% of lung carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for lung carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and lung carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 3.19% of endometrial carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for endometrial carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and endometrial carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 2.92% of bladder carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for bladder carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and bladder carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 2.3% of malignant uterine neoplasm patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for malignant uterine neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and malignant uterine neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 1.95% of malignant salivary gland neoplasm patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for malignant salivary gland neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and malignant salivary gland neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 1.69% of B-cell non-hodgkin lymphoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for B-cell non-hodgkin lymphoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and B-cell non-hodgkin lymphoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 1.33% of soft tissue sarcoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for soft tissue sarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and soft tissue sarcoma as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is altered in 0.96% of lymphoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for lymphoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and lymphoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 1.37% of malignant germ cell tumor patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for malignant germ cell tumor, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and malignant germ cell tumor as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is altered in 0.89% of gastric carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for gastric carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and gastric carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.89% of thyroid gland carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for thyroid gland carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and thyroid gland carcinoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 0.74% of hepatobiliary neoplasm patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for hepatobiliary neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and hepatobiliary neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.74% of malignant hepatobiliary neoplasm patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for malignant hepatobiliary neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and malignant hepatobiliary neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 0.65% of leukemia patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for leukemia, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and leukemia as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is altered in 0.71% of prostate carcinoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for prostate carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and prostate carcinoma as inclusion criteria, 1 is phase 3 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for acute lymphoblastic leukemia, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and acute lymphoblastic leukemia as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for bile duct carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and bile duct carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for bronchogenic carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and bronchogenic carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for cervical carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and cervical carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for cholangiocarcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and cholangiocarcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for chondrosarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and chondrosarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for chronic myeloid leukemia, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and chronic myeloid leukemia as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for classical hodgkin lymphoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and classical hodgkin lymphoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for desmoid-type fibromatosis, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and desmoid-type fibromatosis as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for diffuse intrinsic pontine glioma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and diffuse intrinsic pontine glioma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for esophageal squamous cell carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and esophageal squamous cell carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for Ewing sarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and Ewing sarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for gallbladder carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and gallbladder carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for head and neck carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and head and neck carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for hematologic and lymphocytic disorder, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and hematologic and lymphocytic disorder as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for hematopoietic and lymphoid malignancy, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and hematopoietic and lymphoid malignancy as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for hematopoietic and lymphoid system neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and hematopoietic and lymphoid system neoplasm as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for histiocytic and dendritic cell neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and histiocytic and dendritic cell neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for lip and oral cavity carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and lip and oral cavity carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is altered in 1.32% of liposarcoma patients [3].

PDGFRA is an inclusion criterion in 1 clinical trial for liposarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and liposarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for malignant laryngeal neoplasm, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and malignant laryngeal neoplasm as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for myelodysplastic syndrome with excess blasts-2, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and myelodysplastic syndrome with excess blasts-2 as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for myelodysplastic syndromes, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and myelodysplastic syndromes as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for nasal cavity and paranasal sinus carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and nasal cavity and paranasal sinus carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for nasopharyngeal carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and nasopharyngeal carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for oropharyngeal carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and oropharyngeal carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for oropharyngeal squamous cell carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and oropharyngeal squamous cell carcinoma as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for pecoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and pecoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for penile carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and penile carcinoma as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for peritoneal mesothelioma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and peritoneal mesothelioma as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for systemic mastocytosis, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and systemic mastocytosis as inclusion criteria, 1 is phase 1 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for thymic carcinoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and thymic carcinoma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for undifferentiated pleomorphic sarcoma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and undifferentiated pleomorphic sarcoma as inclusion criteria, 1 is phase 1/phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for WHO grade II glioma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and WHO grade II glioma as inclusion criteria, 1 is phase 2 (1 open) [4].

PDGFRA is an inclusion criterion in 1 clinical trial for WHO grade III glioma, of which 1 is open and 0 are closed. Of the trial that contains PDGFRA status and WHO grade III glioma as inclusion criteria, 1 is phase 2 (1 open) [4].