Associated Diseases


Gene Location [1]
Variant Type

Significance of CD19 Expression in Diseases

B-Cell Acute Lymphoblastic Leukemia +

Diffuse Large B-Cell Lymphoma +

Acute Lymphoblastic Leukemia +

B-Cell Non-Hodgkin Lymphoma +

Chronic Lymphocytic Leukemia +

Non-Hodgkin Lymphoma +

Mantle Cell Lymphoma +

Follicular Lymphoma +

Transformed Non-Hodgkin Lymphoma +

Primary Mediastinal B-Cell Lymphoma +

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma +

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified +

Burkitt Lymphoma +

Lymphoma +

Richter Syndrome +

Small Lymphocytic Lymphoma +

High Grade B-Cell Lymphoma, Not Otherwise Specified +

Mediastinal Large B-Cell Lymphoma +

Double-Hit Lymphoma +

Hairy Cell Leukemia +

Leukemia +

Marginal Zone Lymphoma +

Triple-Hit Lymphoma +

Acute Leukemia +

B-Cell Lymphoblastic Lymphoma +

B-Cell Prolymphocytic Leukemia +

Classical Hodgkin Lymphoma +

Hairy Cell Leukemia Variant +

High Grade B-Cell Lymphoma With MYC And BCL2 And/Or BCL6 Rearrangements +

Hodgkin Lymphoma +

Lymphoplasmacytic Lymphoma +

Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma +

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma +

Waldenstrom Macroglobulinemia +

Acute Biphenotypic Leukemia +

B-Cell Lymphoblastic Leukemia/Lymphoma +

B-Cell Neoplasm +

Central Nervous System Leukemia +

Chronic Myeloid Leukemia +

Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation +

EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified +

Extranodal Marginal Zone Lymphoma Of Mucosa-Associated Lymphoid Tissue +

Grade 3b Follicular Lymphoma +

Hematopoietic And Lymphoid Malignancy +

Indolent Non-Hodgkin Lymphoma +

Mature B-Cell Lymphoma/Leukemia +

Mediastinal Lymphoma +

Nodal Marginal Zone Lymphoma +

Primary Central Nervous System Lymphoma +

Small Lymphocytic Leukemia +

Splenic Marginal Zone Lymphoma +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. Liu X, Wu C, Li C, and Boerwinkle E. dbNSFP v3.0: A one-stop database of functional predictions and annotations for human nonsynonymous and splice site SNVs. Human Mutation. 2015;37:235-241.

Liu X, Jian X, and Boerwinkle E. dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions. Human Mutation. 2011;32:894-899.

4. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 8. This dataset does not represent the totality of the genetic landscape; see paper for more information.

5. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.