Associated Genetic Biomarkers
Associated Diseases


Location [1]
Protein [2]
B-lymphocyte antigen CD20
Synonyms [1]
CVID5, B1, Bp35, CD20, S7, LEU-16, MS4A2

Significance of MS4A1 in Diseases

Diffuse Large B-Cell Lymphoma +

Follicular Lymphoma +

B-Cell Non-Hodgkin Lymphoma +

Mantle Cell Lymphoma +

Non-Hodgkin Lymphoma +

Transformed Non-Hodgkin Lymphoma +

Chronic Lymphocytic Leukemia +

Marginal Zone Lymphoma +

Burkitt Lymphoma +

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma +

Primary Mediastinal B-Cell Lymphoma +

Hodgkin Lymphoma +

Acute Lymphoblastic Leukemia +

Lymphoma +

B-Cell Acute Lymphoblastic Leukemia +

Extranodal Marginal Zone Lymphoma Of Mucosa-Associated Lymphoid Tissue +

Grade 3b Follicular Lymphoma +

Lymphoblastic Lymphoma +

Mediastinal Large B-Cell Lymphoma +

Small Lymphocytic Lymphoma +

Waldenstrom Macroglobulinemia +

High Grade B-Cell Lymphoma, Not Otherwise Specified +

Lymphoplasmacytic Lymphoma +

Mature B-Cell Lymphoma/Leukemia +

Multiple Myeloma +

Nodal Marginal Zone Lymphoma +

Splenic Marginal Zone Lymphoma +

Acute Myeloid Leukemia +

B-Cell Neoplasm +

Double-Hit Lymphoma +

Grade 3 Follicular Lymphoma +

Post-Transplant Lymphoproliferative Disorder +

Primary Central Nervous System Lymphoma +

Richter Syndrome +

T-Cell Non-Hodgkin Lymphoma +

B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma +

Burkitt Leukemia +

Classical Hodgkin Lymphoma +

Grade 1 Follicular Lymphoma +

Grade 2 Follicular Lymphoma +

Hairy Cell Leukemia +

Indolent Non-Hodgkin Lymphoma +

Mediastinal B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma And Classical Hodgkin Lymphoma +

T-Cell/Histiocyte-Rich Large B-Cell Lymphoma +

Triple-Hit Lymphoma +

Anaplastic Large Cell Lymphoma +

Angioimmunoblastic T-Cell Lymphoma +

B-Cell Lymphoblastic Lymphoma +

B-Cell Prolymphocytic Leukemia +

Central Nervous System Lymphoma +

Chronic Myeloid Leukemia +

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified +

Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma +

Hairy Cell Leukemia Variant +

Hematopoietic And Lymphoid Malignancy +

High Grade B-Cell Lymphoma With MYC And BCL2 And/Or BCL6 Rearrangements +

Intraocular Lymphoma +

Lymphoproliferative Disorder +

Malignant Solid Tumor +

Mature B-Cell Non-Hodgkin Lymphoma +

Mature T-Cell And NK-Cell Non-Hodgkin Lymphoma +

Multicentric Angiofollicular Lymphoid Hyperplasia +

Myelodysplastic Syndromes +

Myeloproliferative Neoplasm +

Plasma Cell Leukemia +

Plasmablastic Lymphoma +

Small Cell Lung Carcinoma +

Small Lymphocytic Leukemia +

T-Cell Acute Lymphoblastic Leukemia +


1. Hart R and Prlic A. Universal Transcript Archive Repository. Version uta_20180821. San Francisco CA: Github;2015.

2. The UniProt Consortium. UniProt: a worldwide hub of protein knowledge. Nucleic Acids Research. 2019;47:D506-D515.

3. The AACR Project GENIE Consortium. AACR Project GENIE: powering precision medicine through an international consortium. Cancer Discovery. 2017;7(8):818-831. Dataset Version 6. This dataset does not represent the totality of the genetic landscape; see paper for more information.

4. All assertions and clinical trial landscape data are curated from primary sources. You can read more about the curation process here.